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Marco van Eijk Selected Research

N- (5- adamantane- 1- yl- methoxy- pentyl)deoxynojirimycin

1/2012Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism.
11/2009Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.
2/2009Reduction of glycosphingolipid biosynthesis stimulates biliary lipid secretion in mice.
1/2009Reducing glycosphingolipid content in adipose tissue of obese mice restores insulin sensitivity, adipogenesis and reduces inflammation.
5/2007Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.

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Marco van Eijk Research Topics

Disease

9Insulin Resistance
01/2019 - 05/2007
8Inflammation (Inflammations)
08/2017 - 01/2009
7Gaucher Disease (Gaucher's Disease)
03/2021 - 01/2006
6Obesity
04/2021 - 05/2007
3Infections
11/2015 - 06/2009
3Body Weight (Weight, Body)
10/2014 - 02/2009
3Atherosclerosis
02/2011 - 04/2010
3Type 2 Diabetes Mellitus (MODY)
11/2009 - 05/2007
2Multiple Sclerosis
04/2021 - 04/2010
2Cardiovascular Diseases (Cardiovascular Disease)
04/2021 - 08/2010
2Lysosomal Storage Diseases (Lysosomal Storage Disease)
03/2021 - 01/2020
2Fabry Disease (Fabry's Disease)
01/2020 - 08/2016
2Melanoma (Melanoma, Malignant)
01/2016 - 10/2014
2Fibrosis (Cirrhosis)
01/2015 - 01/2012
1Globoid Cell Leukodystrophy (Krabbe Disease)
01/2020
1GM2 Gangliosidoses (GM2 Gangliosidosis)
01/2020
1Metachromatic Leukodystrophy (Sulfatide Lipidosis)
01/2020
1Mucopolysaccharidosis VII (Sly Syndrome)
08/2017
1Neoplasms (Cancer)
08/2017
1Type C Niemann-Pick Disease (Niemann Pick Disease, Type C)
03/2016
1Granuloma
11/2015
1Arthritis (Polyarthritis)
11/2015
1Pneumonia (Pneumonitis)
11/2015
1Synucleinopathies
01/2015
1Cerebellar Ataxia (Dysmetria)
01/2015
1Motor Disorders
01/2015
1Ischemia
01/2015
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2015
1Ataxia (Dyssynergia)
01/2015
1Lens Subluxation
01/2012
1Aortic Diseases
01/2012
1Fatty Liver
01/2012
1Vascular Diseases (Vascular Disease)
02/2011
1Atherosclerotic Plaque (Atheroma)
02/2011
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2011
1Autoimmune Diseases (Autoimmune Disease)
08/2010
1Hyperglycemia
01/2010
1Leprosy (Hansen's Disease)
06/2009
1Hepatocellular Carcinoma (Hepatoma)
02/2009
1Rupture
12/2006
1Asthma (Bronchial Asthma)
01/2006
1Invasive Fungal Infections
11/2005

Drug/Important Bio-Agent (IBA)

7Glucosylceramides (Glucocerebrosides)IBA
03/2021 - 01/2006
6GlycosphingolipidsIBA
01/2020 - 05/2007
5LipidsIBA
04/2021 - 01/2006
5EnzymesIBA
08/2017 - 01/2006
5N- (5- adamantane- 1- yl- methoxy- pentyl)deoxynojirimycinIBA
01/2012 - 05/2007
4Glucosylceramidase (Glucocerebrosidase)IBA
03/2021 - 01/2006
4ceramide glucosyltransferaseIBA
03/2016 - 05/2007
4Insulin (Novolin)FDA Link
11/2009 - 05/2007
3CholesterolIBA
03/2021 - 02/2009
3CytokinesIBA
11/2015 - 08/2010
2CeramidesIBA
01/2019 - 05/2007
2LeptinIBA
01/2016 - 01/2009
2Glycoproteins (Glycoprotein)IBA
01/2016 - 10/2014
2Triglycerides (Triacylglycerol)IBA
01/2016 - 02/2009
2IgA receptor (protein B)IBA
01/2016 - 10/2014
2Interleukin-4 (Interleukin 4)IBA
10/2014 - 01/2010
2Pharmaceutical PreparationsIBA
08/2010 - 12/2006
2Glucose (Dextrose)FDA LinkGeneric
01/2009 - 05/2007
1sphingosyl beta-glucosideIBA
03/2021
1SphingomyelinsIBA
03/2021
1heparanaseIBA
08/2017
1GlucuronidaseIBA
08/2017
1SphingolipidsIBA
01/2017
1sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
08/2016
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016
1ProteomeIBA
01/2016
1Small Interfering RNA (siRNA)IBA
01/2016
1Fatty Acids (Saturated Fatty Acids)IBA
01/2016
1Biomarkers (Surrogate Marker)IBA
01/2016
1Proteins (Proteins, Gene)FDA Link
11/2015
1CollagenIBA
01/2015
1Calcium-Binding ProteinsIBA
01/2015
1Dexamethasone (Maxidex)FDA LinkGeneric
11/2013
1Macrophage Colony-Stimulating FactorIBA
01/2012
1HLA-DRB1 Chains (HLA DRB1)IBA
01/2012
1HLA-DRB5 Chains (HLA DRB5)IBA
01/2012
1Prolactin Receptors (Prolactin Receptor)IBA
02/2011
1ProlactinIBA
02/2011
1Messenger RNA (mRNA)IBA
02/2011
1LipopolysaccharidesIBA
08/2010
1Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric
08/2010
1Chemotactic FactorsIBA
08/2010
1Azathioprine (Imuran)FDA LinkGeneric
08/2010
1Apolipoprotein E3IBA
08/2010
1ProdrugsIBA
08/2010
11-Deoxynojirimycin (1 Deoxynojirimycin)IBA
01/2010
1Interleukin-13IBA
01/2010
1chitotriosidaseIBA
06/2009
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
02/2009
1SterolsIBA
02/2009
1OsteopontinIBA
01/2009
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2009
1PhosphatidylserinesIBA
12/2006
1O-methyl-serine dodecylamide hydrochlorideIBA
12/2006
1Serine (L-Serine)FDA Link
12/2006
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2005

Therapy/Procedure

2Therapeutics
06/2009 - 05/2007
1Lasers (Laser)
01/2016